Prevalence, specificity and significance of ovarian antibodies during spontaneous premature ovarian failure

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Prevalence, specificity and significance of ovarian antibodies during spontaneous premature ovarian failure.

Autoimmunity may be involved in idiopathic premature ovarian failure (POF). However, the frequency, physiopathology and potential reversibility of autoimmune oophoritis needs clarification. Using an ELISA against whole tissue homogenate as antigen, from human ovaries at different ages, positive circulating ovarian antibodies (AOA) were found in 59% of patients with primitive idiopathic POF (27/...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 1997

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/12.12.2623